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hcn4 subunit  (Alomone Labs)


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    Structured Review

    Alomone Labs hcn4 subunit
    Immunoperoxidase labeling of HCN subunits in human nucleus raphe interpositus (RIP). (A) Consecutive 5 μm thick coronal paraffin sections through RIP stained for HCN1 (left) and HCN2 (right). HCN1 (left) is labeled only in OPNs, which are ensheathed by perineuronal nets (red arrows) and lacks completely in cholinergic non-OPNs (green arrows) (middle). On the other hand, HCN2 (right) immunolabeling is found in both neuron groups. (B) <t>HCN4</t> immunolabeling (right) is ubiquitously found both in OPNs (red arrows) in cholinergic non-OPNs (green arrows). Scale bar represents 50 μm.
    Hcn4 Subunit, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hcn4 subunit/product/Alomone Labs
    Average 94 stars, based on 10 article reviews
    hcn4 subunit - by Bioz Stars, 2026-03
    94/100 stars

    Images

    1) Product Images from "Transmitter and ion channel profiles of saccadic omnipause neurons and cholinergic non-omnipause neurons in human nucleus raphe interpositus"

    Article Title: Transmitter and ion channel profiles of saccadic omnipause neurons and cholinergic non-omnipause neurons in human nucleus raphe interpositus

    Journal: Frontiers in Neuroanatomy

    doi: 10.3389/fnana.2025.1670220

    Immunoperoxidase labeling of HCN subunits in human nucleus raphe interpositus (RIP). (A) Consecutive 5 μm thick coronal paraffin sections through RIP stained for HCN1 (left) and HCN2 (right). HCN1 (left) is labeled only in OPNs, which are ensheathed by perineuronal nets (red arrows) and lacks completely in cholinergic non-OPNs (green arrows) (middle). On the other hand, HCN2 (right) immunolabeling is found in both neuron groups. (B) HCN4 immunolabeling (right) is ubiquitously found both in OPNs (red arrows) in cholinergic non-OPNs (green arrows). Scale bar represents 50 μm.
    Figure Legend Snippet: Immunoperoxidase labeling of HCN subunits in human nucleus raphe interpositus (RIP). (A) Consecutive 5 μm thick coronal paraffin sections through RIP stained for HCN1 (left) and HCN2 (right). HCN1 (left) is labeled only in OPNs, which are ensheathed by perineuronal nets (red arrows) and lacks completely in cholinergic non-OPNs (green arrows) (middle). On the other hand, HCN2 (right) immunolabeling is found in both neuron groups. (B) HCN4 immunolabeling (right) is ubiquitously found both in OPNs (red arrows) in cholinergic non-OPNs (green arrows). Scale bar represents 50 μm.

    Techniques Used: Labeling, Staining, Immunolabeling



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    hcn4 subunit  (Alomone Labs)
    94
    Alomone Labs hcn4 subunit
    Immunoperoxidase labeling of HCN subunits in human nucleus raphe interpositus (RIP). (A) Consecutive 5 μm thick coronal paraffin sections through RIP stained for HCN1 (left) and HCN2 (right). HCN1 (left) is labeled only in OPNs, which are ensheathed by perineuronal nets (red arrows) and lacks completely in cholinergic non-OPNs (green arrows) (middle). On the other hand, HCN2 (right) immunolabeling is found in both neuron groups. (B) <t>HCN4</t> immunolabeling (right) is ubiquitously found both in OPNs (red arrows) in cholinergic non-OPNs (green arrows). Scale bar represents 50 μm.
    Hcn4 Subunit, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hcn4 subunit/product/Alomone Labs
    Average 94 stars, based on 1 article reviews
    hcn4 subunit - by Bioz Stars, 2026-03
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    Immunoperoxidase labeling of HCN subunits in human nucleus raphe interpositus (RIP). (A) Consecutive 5 μm thick coronal paraffin sections through RIP stained for HCN1 (left) and HCN2 (right). HCN1 (left) is labeled only in OPNs, which are ensheathed by perineuronal nets (red arrows) and lacks completely in cholinergic non-OPNs (green arrows) (middle). On the other hand, HCN2 (right) immunolabeling is found in both neuron groups. (B) HCN4 immunolabeling (right) is ubiquitously found both in OPNs (red arrows) in cholinergic non-OPNs (green arrows). Scale bar represents 50 μm.

    Journal: Frontiers in Neuroanatomy

    Article Title: Transmitter and ion channel profiles of saccadic omnipause neurons and cholinergic non-omnipause neurons in human nucleus raphe interpositus

    doi: 10.3389/fnana.2025.1670220

    Figure Lengend Snippet: Immunoperoxidase labeling of HCN subunits in human nucleus raphe interpositus (RIP). (A) Consecutive 5 μm thick coronal paraffin sections through RIP stained for HCN1 (left) and HCN2 (right). HCN1 (left) is labeled only in OPNs, which are ensheathed by perineuronal nets (red arrows) and lacks completely in cholinergic non-OPNs (green arrows) (middle). On the other hand, HCN2 (right) immunolabeling is found in both neuron groups. (B) HCN4 immunolabeling (right) is ubiquitously found both in OPNs (red arrows) in cholinergic non-OPNs (green arrows). Scale bar represents 50 μm.

    Article Snippet: HCN4 subunit was detected with polyclonal guinea pig antibody (Cat #: APC-052-GP (formerly AGP-004); RRID: AB_2340957; Alomone Labs, Jerusalem, Israel), which recognizes an intracellular epitope at the N-terminus, corresponding to amino acid residues 119–155 of human HCN4.

    Techniques: Labeling, Staining, Immunolabeling